Hand washing killed C diff
What is C diff? C diff is the nickname of Clostridium difficile colitis. C diff is a bacteria with a hard crust that classifies it a spore bacteria.
· What are the symptoms?
· The symptoms are similar to flu symptoms.
· Typically comes on quickly within 24 hours.
· Adult patients will have three or more watery or partly formed stools. Children may experience two to three watery stools over several days.
· Recent use of antibiotics.
· Complaints of abdominal pain, may be nausea, and have loss of appetite.
· Fevers of 105 degrees Fahrenheit or 40.5 Celsius.
· Stool has a distinctive smell.
· A slight rise in white blood cell count up from a normal 10,000 to 15,000 or higher.
How do you get C diff?
· Transmitted from human to human via fecal-oral route.
· Gastric acid suppression medications.
· Antibiotics; fluroquinolone, cephalosporins, carbpenems, and clindamycin.
· Overuse of antibiotics in meat sources.
· Unclean healthcare environments.
How is C diff diagnosed?
· Cytotoxicity assay : Gold standard of diagnosis is a toxigenic culture. Stool sample grown in a petri dish and tested for toxin production. This is slow and can take up to 72 hours but remains the highest in sensitivity and specificity.
· Toxin ELISA is an immounosorbent assay and detect toxin A, B, or both with negative prediction of 96%
· Stool sample: testing for leukocyte and lactoferrin levels. Limited accuracy.
· Stool sample: Polymerase chain reaction and 90% accurate.
How do you kill C diff?
· Hand washing with soap and water. Friction breaks down the crust on the spore and allows it to be killed. Alcohol gels do not break down the crust. Hand washing between patients will prevent the spread of C diff to other patients and to health personnel.
· Medication of choice is the inexpensive Metronidazole first.
· Second medication is oral Vancomycin or in addition to Metronidazole.
· Avoiding long term antibiotic medications to decrease diarrhea to avoid worsening C diff.
· Probiotics, evidenced-based research is showing positive results in re-establishing GI flora and decreasing C diff.
· Sever cases, stool transplant or surgery.
How long will it take to get better?
· 3-5 days after treatment, symptoms will resolve in 10 days.
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